We specialized designed and manufacture of Soft Gelatin equipment and Plant with covering all the process with latest cGMP norms.
SPECIFICATIONS OF SOFT GELATIN PLANT , GELATIN MELTING SYSTEM AND PLANT
APPLICATIONS - PROCESSING AND MANUFACTURING OF SOFT GELATIN CAPSULES
Gelatin processing systems for batch sizes ranging from 10 L to 5,000 L are suitable to manufacture different types of Gelatin compounds like soft gelatin, hard gelatin, HPMC / Wet gelatin and other similar products. We offer completely customized systems adhering to cGMP and ASME BPE guidelines for aseptic manufacturing.
We offer a full range of process vessels and their automation - comprising optional SCADA package - as well as all associated peripherals including suction pumps, CIP/SIP systems, and the stand mounted stirrer assembly.
A standard gelatin capsule manufacturing takes place in two different vessels – A gelatin melting tank and a medicine mixer. Other components may include an emulsifier/homogenizer, a vacuum pump, Transfer pump, storage and buffer vessels and a CIP module. All our vessels are made of SS316L grade material and fabricated as per cGMP guidelines. The plant can be completely automated with pneumatically operated valves for aseptic manufacturing.
Mixing and melting of gelatin, purified water & glycerin is carried out in the gelatin melting vessel. Each product is sucked into the vessel at vacuum pressure for minimum contamination. The vessel is jacketed for heating & cooling of the solution in the vessel. For uniform mixing, an anchor type stirrer is utilized along with Teflon scrapers. A high shear mixer or emulsifier is used to reduce the particle size of gelatin powder to less than 5 microns. The contents can also be recalculated back into the vessel via a transfer pump based on the product viscosity. Desecration of the solution is also done during heating. After obtaining the satisfied composition, the contents of the vessel are transferred to a gelatin holding vessel.
The contents of the medicine in the final product is prepared in the medicine mixer. The ingredients are sucked into the vessel at vacuum pressure for minimum contamination. The vessel is jacketed for heating & cooling of the solution in the vessel. For uniform mixing, an anchor type stirrer is utilized along with Teflon scrapers. After obtaining the satisfied composition, the contents of the vessel are transferred to a medicine holding vessel via a transfer pump.
The operations of various pumps, pneumatically operated valves (in case of automated operation) and mixers is carried out through the main control panel. The panel is made out of SS304 grade material and consists of various safety lock systems like the Emergency stop and Mains supply indicators for safe work and extended component life. The vessels are connected to each other via interconnecting pipelines manufactured as per cGMP norms and connected with sealed tri clamp connection.